Introduction
Dexedrine and Adderall are two commonly prescribed stimulants used to treat attention-deficit hyperactivity disorder (ADHD). Both drugs belong to the same drug class, known as central nervous system stimulants, and share many similarities. However, there are also some key differences between the two drugs, which can affect their efficacy and side effects profiles.
Active Ingredients
Dexedrine contains the active ingredient dextroamphetamine, while Adderall contains a combination of dextroamphetamine and levoamphetamine. This difference in active ingredients can result in some variations in the effects of the two drugs.
Formulations
Dexedrine is available in both immediate-release (IR) and extended-release (ER) formulations. Adderall is also available in both IR and ER formulations, as well as a chewable tablet formulation for children.
Dosing
The dosage of Dexedrine or Adderall will vary depending on the individual’s needs and the specific formulation being used. It is important to follow the dosing instructions provided by your doctor or pharmacist.
Onset and Duration of Action
Dexedrine IR has a rapid onset of action, typically within 30 minutes, and a duration of action of 4-6 hours. Adderall IR has a similar onset of action but a slightly longer duration of action, typically 6-8 hours. Dexedrine ER and Adderall ER have a slower onset of action and a longer duration of action, typically 12-14 hours.
Efficacy
Both Dexedrine and Adderall have been shown to be effective in treating ADHD. Studies have shown that both drugs can improve attention and focus, reduce hyperactivity and impulsivity, and enhance academic performance and social behavior in children and adults with ADHD.
Side Effects
The most common side effects of Dexedrine and Adderall include:
- Increased heart rate
- Increased blood pressure
- Insomnia
- Anxiety
- Headache
- Nausea
- Dry mouth
Contraindications
Dexedrine and Adderall are not recommended for people with a history of:
- Heart disease
- Stroke
- Severe high blood pressure
- Seizures
- Psychosis
- Drug or alcohol abuse
Drug Interactions
Dexedrine and Adderall can interact with other medications, including:
- Antidepressants
- Antipsychotics
- Blood thinners
- Seizure medications
- Antihistamines
Abuse Potential
Both Dexedrine and Adderall have a high potential for abuse. People who abuse these drugs may experience:
- Euphoria
- Increased energy
- Decreased appetite
- Talkativeness
- Dilated pupils
- Sweating
- Shakiness
Which Drug Is Right for Me?
The choice of which drug, Dexedrine or Adderall, is right for you will depend on a number of factors, including your individual needs, the severity of your ADHD symptoms, and your response to previous stimulant medications. Your doctor can help you determine which drug is the best option for you.
Conclusion
Dexedrine and Adderall are two effective stimulants used to treat ADHD. Both drugs have similar efficacy and side effects profiles, but there are some key differences between the two drugs, including their active ingredients, formulations, dosing, onset and duration of action, and potential for abuse. Your doctor can help you determine which drug is the best option for you.